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Captain America (1968 1st Series) #344

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Ronald Reagan cameo; 52-page giant. "Don't Tread On Me!" Giant-size issue. Story by Mark Gruenwald. Art by Kieron Dwyer and Al Milgrom. Cover by Ron Frenz and Al Milgrom.

It's chaos in the streets as the residents of Washington D.C. are turning into human serpents after the Cobra, Copperhead, and Boomslang successfully poison the water supply! And now the Viper is storming the White House! The Captain busts into the Oval Office to battle the Viper...and the President? Also in this issue, Captain America (aka John Walker) and Bucky fight Diamondback and the Demolition Man. Cameo appearances by President Ronald Reagan and first lady Nancy Reagan.